Ellen DeGeneres is heading back to where it all began, give or take a few million people.

The award-winning talk show host has been tapped to preside over the upcoming TBS variety special Ellen's Really Big Show, which will feature stand-up comedy, musical acts and DeGeneres' signature brand of giggle-inducement.

The two-hour show, to be culled from footage shot during the HBO Comedy Festival taking place Nov. 14-17 at Caesars Palace in Las Vegas, airs Nov. 18 on TBS. The Time Warner-owned cable network is the festival's title sponsor.